{"id":2044,"date":"2023-10-30T13:35:19","date_gmt":"2023-10-30T13:35:19","guid":{"rendered":"https:\/\/tris.sambrownprojects.com\/?p=2044"},"modified":"2023-11-30T11:06:43","modified_gmt":"2023-11-30T11:06:43","slug":"tris-pharma-partners-with-perigon-pharmacy-360-to-enhance-access-to-dyanavel-xr-tablets-for-the-treatment-of-attention-deficit-hyperactivity-disorder","status":"publish","type":"post","link":"https:\/\/www.trispharma.com\/tris-pharma-partners-with-perigon-pharmacy-360-to-enhance-access-to-dyanavel-xr-tablets-for-the-treatment-of-attention-deficit-hyperactivity-disorder\/","title":{"rendered":"Tris Pharma Partners with Perigon Pharmacy 360 to Enhance Access to DYANAVEL\u00ae XR Tablets for the Treatment of Attention Deficit Hyperactivity Disorder"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<\/p>\n<p style=\"text-align: center;\"><em>\u2013 National direct-to-patient program allows patients and caregivers to obtain DYANAVEL XR extended-release tablet prescriptions from digital pharmacy \u2013 <\/em><\/p>\n<p>MONMOUTH JUNCTION, NJ, October 30, 2023\u00a0\u2013 Tris Pharma, Inc. (Tris), a commercial-stage biopharmaceutical company focused on attention deficit hyperactivity disorder (ADHD), pain, addiction and neurological disorders, today announced a new partnership with Perigon Pharmacy 360, a full-service, specialty digital pharmacy, to enhance accessibility, affordability and adherence for patients treating symptoms of ADHD with Tris\u2019 DYANAVEL<sup>\u00ae<\/sup>\u00a0XR (amphetamine) extended-release tablets.<\/p>\n<p>Together, Tris Pharma and Perigon launched a direct-to-patient program, DYANAVEL Delivered, that allows patients and caregivers to seamlessly access DYANAVEL XR extended-release tablets through Perigon\u2019s digital pharmacy, enhance their medication management, and receive reimbursement assistance and support to help navigate their treatment journey while reducing administrative burden for both patients and providers. The program is available across the United States, enabling nationwide access to DYANAVEL XR extended-release tablets. Patients and physicians wishing to access the DYANAVEL Delivered program can learn more at\u00a0<a href=\"https:\/\/www.dyanavel.com\/delivered\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">www.dyanavel.com\/delivered<\/a>.<\/p>\n<p>\u201cThis partnership underscores our continued commitment to ensuring patients have access to the medications they need to treat their ADHD symptoms,\u201d said Ketan Mehta, founder and CEO at Tris Pharma. \u201cIn an environment where shortages have been significant and widespread for more than a year, Tris Pharma is among the relatively few companies that have managed to not only maintain but increase supply of our ADHD medications without interruption. Our program with Perigon builds on this success by offering patients a more convenient way to consistently obtain access to their DYANAVEL XR extended-release tablet prescription.\u201d<\/p>\n<p>Since the November 2021 approval of DYANAVEL XR extended-release tablets, Tris Pharma has seen a consistent increase in prescription volume and taken steps to manage manufacturing volume to ensure that the company is able to consistently meet and exceed demand. The DYANAVEL Delivered program is designed to help eliminate bottlenecks by delivering DYANAVEL XR extended-release tablets directly to patients and caregivers.<\/p>\n<p>\u201cWe\u2019re incredibly excited to partner with Tris Pharma on this program, because we believe it has the potential to enhance quality of care and reduce prescription access challenges for ADHD patients during a particularly critical time,\u201d said Ted Mills, CEO at Perigon Pharmacy 360. \u201cAdditionally, this partnership will provide important insights about the impact of innovative technology and advanced healthcare solutions on real-world patient outcomes.\u201d<\/p>\n<p>DYANAVEL XR extended-release tablets are approved for the treatment of ADHD in patients aged 6 years and older. This medication is developed using Tris Pharma\u2019s proprietary Liqui<em>XR<\/em><sup>\u00ae<\/sup>\u00a0technology to create a non-degrading diffusion coating that offers a consistent, controlled release of medication over time.<\/p>\n<p><strong>DYANAVEL XR is a federally controlled substance (CII) because it contains amphetamine that can be a target for people who abuse prescription medicines or street drugs.<\/strong>\u00a0Keep DYANAVEL XR in a safe place to protect it from theft. Never give your DYANAVEL XR to anyone else because it may cause death or harm them. Selling or giving away DYANAVEL XR may harm others and is against the law. See additional important safety information below.<\/p>\n<p><strong>About Tris Pharma<\/strong><\/p>\n<p>Tris Pharma is a privately held, innovation-driven biopharmaceutical company that is applying its drug development capabilities and proprietary technologies to transform the treatment of ADHD, pain and neurological disorders, including addiction and diseases of the central nervous system. Tris is an established commercial organization with a robust portfolio of best-in-class ADHD products and a promising pipeline of differentiated, near-term drug candidates. More information is available at\u00a0<a href=\"https:\/\/www.trispharma.com\/\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">www.trispharma.com<\/a>\u00a0and on LinkedIn\u00a0<a href=\"https:\/\/www.linkedin.com\/company\/trispharma\/\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">@TrisPharma<\/a>.<\/p>\n<p><strong>About Perigon Pharmacy 360<\/strong><\/p>\n<p>Perigon Pharmacy 360 is an independent specialty pharmacy that is working to provide care and support to those in need. Perigon serves patients in all 50 states, plus D.C., and are focused on helping improve the patient experience through access to medications, caregiver awareness, provider engagement, and clinical support of our Care Teams. Perigon also utilizes the proprietary Medesto platform, together with the specialty and traditional care pharmacy, to create a Precision Digital Pharmacy model with the goal of improving medication adherence and, clinical outcomes. Perigon Pharmacy 360 is redefining the manner in which patients interact with the critical role of the Pharmacist. For more information, please visit\u00a0<a href=\"https:\/\/www.perigonpharmacy.org\/\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">www.perigonpharmacy.org<\/a><\/p>\n<p><strong>INDICATION<\/strong><\/p>\n<p>DYANAVEL XR is indicated for the treatment of attention deficit hyperactivity disorder (ADHD) in patients 6 years and older.<\/p>\n<p><strong>IMPORTANT SAFETY INFORMATION<\/strong><\/p>\n<p><strong>WARNING: ABUSE, MISUSE, AND ADDICTION<\/strong><br \/>\n<strong>DYANAVEL XR has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including DYANAVEL XR, can result in overdose and death. Before prescribing DYANAVEL XR, assess each patient\u2019s risk for abuse, misuse, and addiction. Educate patients and their families about these risks, proper storage of the drug, and proper disposal of any unused drug. Throughout treatment, reassess each patient\u2019s risk and frequently monitor for signs and symptoms of abuse, misuse, and addiction.<\/strong><\/p>\n<ul>\n<li>DYANAVEL XR is contraindicated:\n<ul>\n<li>In patients known to be hypersensitive to amphetamine, or other components of DYANAVEL XR. Hypersensitivity reactions, such as angioedema and anaphylactic reactions, have been reported with other amphetamines.<\/li>\n<li>in patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of increased risk of hypertensive crisis.<\/li>\n<\/ul>\n<\/li>\n<li>Sudden death has been reported in patients with structural cardiac abnormalities or other serious cardiac disease who were treated with CNS stimulants at the recommended ADHD doses. Serious cardiovascular effects with overdose may precipitate sudden cardiac death. Prior to treating patients with DYANAVEL XR, assess for the presence of cardiac disease. Avoid DYANAVEL XR use in patients with known structural cardiac abnormalities, cardiomyopathy, serious cardiac arrhythmia, coronary artery disease, or other serious cardiac disease Further evaluate patients who develop exertional chest pain, unexplained syncope, or arrhythmias during DYANAVEL XR treatment.<\/li>\n<li>CNS stimulants cause increase in blood pressure (mean increase about 2 to 4 mm Hg) and heart rate (mean increase about 3 to 6 bpm). Monitor all patients for potential tachycardia and hypertension.<\/li>\n<li>Use of CNS stimulants may cause exacerbation of pre-existing psychosis and may induce maniac or mixed episode in patients with bipolar disorder. In patients without prior history of psychotic illness or mania, CNS stimulants may cause new psychotic or manic symptoms (e.g., hallucinations, delusional thinking, or mania) at the recommended dosage. Prior to initiating DYANAVEL XR treatment, screen patients for risk factors for developing a manic episode. If new psychotic or manic symptoms occur, consider discontinuing DYANAVEL XR.<\/li>\n<li>CNS stimulants have been associated with weight loss and slowing of growth rate in pediatric patients with ADHD; monitor weight and height during treatment with DYANAVEL XR. Treatment may need to be interrupted in children not growing as expected.<\/li>\n<li>CNS stimulants, including DYANAVEL XR, are associated with peripheral vasculopathy, including Raynaud\u2019s phenomenon. Signs and symptoms are usually intermittent and mild; very rare sequelae include digital ulceration and\/or soft tissue breakdown. Careful observation for digital changes is necessary during treatment with ADHD stimulants. Further clinical evaluation (e.g., rheumatology referral) may be appropriate for DYANAVEL XR-treated patients who develop signs or symptoms of peripheral vasculopathy.<\/li>\n<li>Serotonin syndrome risk is increased when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), MAOIs, and during overdosage situations. If it occurs, discontinue DYANAVEL XR and any concomitant serotonergic agents immediately, and initiate supportive treatment.<\/li>\n<li>CNS stimulants, including amphetamine, have been associated with the onset or exacerbation of motor and verbal tics. Worsening of Tourette\u2019s syndrome has also been reported. Before initiating DYANAVEL XR, assess the family history and clinically evaluate patients for tics or Tourette\u2019s syndrome. Regularly monitor DYANAVEL XR-treated patients for the emergence or worsening of tics or Tourette\u2019s syndrome and discontinue treatment if clinically appropriate.<\/li>\n<li>Most common adverse reactions observed with amphetamine products: dry mouth, anorexia, weight loss, abdominal pain, nausea, insomnia, restlessness, emotional lability, dizziness, and tachycardia. Based on limited experience with DYANAVEL XR in controlled trials, the adverse reaction profile of DYANAVEL XR appears similar to other amphetamine extended-release products. The most common (\u22652% in the DYANAVEL XR group and greater than placebo) adverse reactions reported in the Phase 3 controlled study conducted in 108 patients with ADHD (aged 6 to 12 years) were: epistaxis (DYANAVEL XR 4%, placebo 0%), allergic rhinitis (4%, 0%) and upper abdominal pain (4%, 2%).<\/li>\n<li>DYANAVEL XR use during pregnancy may cause fetal harm. To monitor pregnancy outcomes in women exposed to DYANAVEL XR during pregnancy, healthcare providers are encouraged to register patients by calling the National Pregnancy Registry for Psychostimulants at 1-866-961-2388 or visiting online at\u00a0<a class=\"no-focus-shift\" href=\"https:\/\/womensmentalhealth.org\/clinical-and-research-programs\/pregnancyregistry\/othermedications\/\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">https:\/\/womensmentalhealth.org\/clinical-and-research-programs\/pregnancyregistry\/othermedications\/<\/a>.<\/li>\n<li>Because of the potential for serious adverse reactions in a breastfed infant, breastfeeding is not recommended during treatment with DYANAVEL XR.<\/li>\n<\/ul>\n<p><strong>To report SUSPECTED ADVERSE REACTIONS, contact Tris Pharma, Inc. at 1-732-940-0358 or FDA at 1-800-FDA-1088 or\u00a0<a href=\"https:\/\/www.fda.gov\/medwatch\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_new_window_message\">www.fda.gov\/medwatch<\/a>.<\/strong><\/p>\n<p><strong>Please see\u00a0<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2023\/208147s016,210526s008lbl.pdf\" target=\"_blank\" rel=\"noopener\" aria-describedby=\"audioeye_pdf_message audioeye_new_window_message\">Full Prescribing Information<\/a>, including Boxed Warning regarding ABUSE, MISUSE, AND ADDICTION.<\/strong><\/p>\n<p>DYANAVEL<sup>\u00ae<\/sup>\u00a0and Liqui<em>XR<\/em><sup>\u00ae<\/sup>\u00a0are registered trademarks of Tris Pharma, Inc.<\/p>\n<p><strong>Company Contact<\/strong><\/p>\n<p>Cheryl Patnick<br \/>\nTris Pharma, Inc.<br \/>\n<a href=\"mailto:cpatnick@trispharma.com\">cpatnick@trispharma.com<\/a><\/p>\n<p><strong>Media Contact<\/strong><\/p>\n<p>Laura Morgan<br \/>\nSam Brown, Inc.<br \/>\n951.333.9110<br \/>\n<a href=\"mailto:lauramorgan@sambrown.com\">lauramorgan@sambrown.com<\/a>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] \u2013 National direct-to-patient program allows patients and caregivers to obtain DYANAVEL XR extended-release tablet prescriptions from digital pharmacy \u2013 MONMOUTH JUNCTION, NJ, October 30, 2023\u00a0\u2013 Tris Pharma, Inc. (Tris), a commercial-stage biopharmaceutical company focused on attention deficit hyperactivity disorder (ADHD), pain, addiction and neurological disorders, today announced a new partnership with Perigon Pharmacy 360, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_wp_rev_ctl_limit":""},"categories":[28],"tags":[],"class_list":["post-2044","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"acf":[],"featured_image_src":{"landsacpe":false,"list":false,"medium":false,"full":false},"yoast_head":"\n<title>Tris Pharma Partners with Perigon Pharmacy 360 to Enhance Access to DYANAVEL\u00ae XR Tablets for the Treatment of Attention Deficit Hyperactivity Disorder - Tris Pharma<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.trispharma.com\/tris-pharma-partners-with-perigon-pharmacy-360-to-enhance-access-to-dyanavel-xr-tablets-for-the-treatment-of-attention-deficit-hyperactivity-disorder\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tris Pharma Partners with Perigon Pharmacy 360 to Enhance Access to DYANAVEL\u00ae XR Tablets for the Treatment of Attention Deficit Hyperactivity Disorder - Tris Pharma\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text] \u2013 National direct-to-patient program allows patients and caregivers to obtain DYANAVEL XR extended-release tablet prescriptions from digital pharmacy \u2013 MONMOUTH JUNCTION, NJ, October 30, 2023\u00a0\u2013 Tris Pharma, Inc. 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